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Article

Allelotyping of acute myelogenous leukemia: loss of heterozygosity at 7q31.1 (D7S486) and q33-34 (D7S498, D7S505).

Leukemia research - 1 Mar 1999

Koike M, Tasaka T, Spira S, Tsuruoka N, Koeffler H P

Abstract excerpt

Loss of a whole chromosome 7(-7) or a deletion of the long arm of chromosome 7 del(7q) occurs frequently in many types of primary cancers including cases of acute myelogenous leukemia (AML). We analyzed for loss of heterozygosity (LOH) of chromosome arm 7q in 26 AML cases using a set of 15 microsatellite markers in order to begin to determine the location of putative tumor suppressor genes (TSG) important to this...

Topics

Alleles
Chromosomes, Human, Pair 7
Humans
Leukemia, Myeloid, Acute
Loss of Heterozygosity

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 10071086
DOI: 10.1016/s0145-2126(98)00159-3

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Allelotyping of acute myelogenous leukemia: loss of heterozygosity at 7q31.1 (D7S486) and q33-34 (D7S498, D7S505).PMID 10071086Read ↗

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