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Article

Envelope and precore/core variants of hepatitis B virus.

Gastroenterology clinics of North America - 1 Sept 1994

Thomas H C, Carman W F

Abstract excerpt

The appearance of replication-competent variants of HBV with mutations in the envelope and precore/core and X proteins emphasizes that these proteins are the focus of immune selection pressures in the human host. The presence of an antibody response in the absence of a CTL response may create the ideal selection environment. This occurs in the early phase of passive/active immunization against HBV envelope...

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PMID: 7989091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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