Article
Envelope and precore/core variants of hepatitis B virus.
Gastroenterology clinics of North America - 1 Sept 1994
Thomas H C, Carman W F
Abstract excerpt
The appearance of replication-competent variants of HBV with mutations in the envelope and precore/core and X proteins emphasizes that these proteins are the focus of immune selection pressures in the human host. The presence of an antibody response in the absence of a CTL response may create the...
Topics
- Acute Disease
- Adult
- Chronic Disease
- DNA, Viral
- Female
- Genetic Variation
- Genome, Viral
- Genotype
- Hepatic Encephalopathy
- Hepatitis B e Antigens
- Hepatitis B virus
- Hepatitis, Viral, Human
- Humans
- Immune Tolerance
- Infant, Newborn
- Protein Biosynthesis
- Viral Core Proteins
- Viral Envelope Proteins
