Variation in the core and X genes of hepatitis B virus.

Abstract excerpt

Variation in viral genomes is dependent upon rates of polymerase error and the relative influence of selection pressures. For HBV, it appears that there is substantial immune pressure in keeping with the immunopathogenesis; the ability of the virus to persist is probably linked with this process. As the viral genome is small, mutants may have multiple effects, particularly apparent within regions that have...

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