Article
A new hepatitis B virus variant in a chronic carrier with multiple episodes of viral reactivation and acute hepatitis.
Virology - 1 Nov 1990
Raimondo G, Schneider R, Stemler M, Smedile V, Rodino G, Will H
Abstract excerpt
To examine whether there are HBV variants not yet described which cannot express HBe due to a mutation in the pre-C region, and, if they exist, whether they cause a particular course of infection and disease, we analyzed the HBV genomes of a HBs/anti-HBe positive chronic carrier who had several episodes of acute reexacerbations of chronic hepatitis with at least two viremic phases. Direct sequencing of the...
Topics
- Adult
- Amino Acid Sequence
- Carrier State
- Genes, Viral
- Genetic Variation
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Male
- Molecular Sequence Data