Article
Hepatitis B virus acquisition and pathogenesis in childhood: host genetic determinants.
Journal of pediatric gastroenterology and nutrition - 1 Jan 2011
Chatzidaki V, Kouroumalis E, Galanakis E
Abstract excerpt
The clinical course of hepatitis B virus (HBV) infection varies from spontaneous recovery to chronic persistent infection leading to severe liver injury. Mounting evidence has recently highlighted the influence of host genotype in the complex interplay between viral and host factors. Studies in adults have suggested the existence of a genetic predisposition to HBV infection secondary to certain defects in the...
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