Article
The emergence of envelope and precore/core variants of hepatitis B virus: the potential role of antibody selection.
Journal of hepatology - 1 Jan 1995
Thomas H C
Abstract excerpt
The appearance of replication-competent variants of hepatitis B virus (HBV) with mutations in the envelope and precore/core proteins emphasizes that these proteins are the focus of immune selection pressure in the human host. The sequence and speed of application of the multiple selection pressur...
Topics
- Genetic Variation
- Hepatitis B Antibodies
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Polymerase Chain Reaction
- Treatment Outcome
- Viral Core Proteins
- Viral Envelope Proteins
- Virus Replication
