Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The emergence of envelope and precore/core variants of hepatitis B virus: the potential role of antibody selection.

Journal of hepatology - 1 Jan 1995

Thomas H C

Abstract excerpt

The appearance of replication-competent variants of hepatitis B virus (HBV) with mutations in the envelope and precore/core proteins emphasizes that these proteins are the focus of immune selection pressure in the human host. The sequence and speed of application of the multiple selection pressures (humoral and possibly cellular) determine the virologic and clinical outcome. When these variant viruses are passed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Variation
Share to Hepatitis B e Antigens
Share to Hepatitis B virus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymerase Chain Reaction

Share to Treatment Outcome

Share to Viral Core Proteins

Share to Viral Envelope Proteins

Share to Virus Replication

Source

Identifiers

PMID: 7602059

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The emergence of envelope and precore/core variants of hepatitis B virus: the potential role of antibody selection.PMID 7602059Read ↗

Envelope and precore/core variants of hepatitis B virus.Semantic proximity Read ↗

The host immune response may be responsible for selection of envelope and precore/core variants of HBV.Semantic proximity Read ↗

The host immune response may be responsible for selection of envelope and precore/core variants of HBV.Semantic proximity Read ↗

Hepatitis B virus replication and mutation are autoregulated by interactions between surface antigen and HBeAg and the HBV DNA polymerase: a functional model with therapeutic implications.Semantic proximity Read ↗

Mathematical investigation of HBeAg seroclearance.Semantic proximity Read ↗

Selection of a precore mutant of hepatitis B virus and reactivation of chronic hepatitis B acquired in childhood.Semantic proximity Read ↗

Antibody V(h) repertoire differences between resolving and chronically evolving hepatitis C virus infections.Semantic proximity Read ↗

Hepatitis B Virus Core Protein Mutations Are Concentrated in B Cell Epitopes in Progressive Disease and in T Helper Cell Epitopes during Clinical RemissionSemantic proximity Read ↗

Reactivation of precore variant hepatitis B virus in a child with severe aplastic anaemia.Semantic proximity Read ↗

Spontaneous seroconversion in chronic hepatitis B: role of mutations in the precore/core gene.Semantic proximity Read ↗

Selection of hepatitis B surface "escape" mutants during passive immune prophylaxis following liver transplantation: potential impact of genetic changes on polymerase protein function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.