Article
[High- and low-risk molecular sequences in autoimmune diseases. An analysis of type I diabetes in Latin America].
Gaceta medica de Mexico - 1 Jan 1997
Gorodezky C, Olivo A, Alaez C, Vázquez M N, de la Rosa G, Debaz H, Robles C, Altamirano N, Layrisse Z, Balducci P L, Domínguez E, Herrera F, Montagnani S, Esparza B, Balbas O, Gunczler P, Lanes R, Amaro R, Zaro R, Fuenmayor V, Montoya F, Bedoya C I, Restrepo M C, Villegas A, Vicario J L
Abstract excerpt
Type I diabetes is an autoimmune and a polygenic disease, in which MHC-class II genes contribute to 48% of the disease. The aim of the present study, is to provide a guideline to understanding the molecular association of these genes, through the immunogenetic analysis of 3 Latin american mestizo...
Topics
- Adolescent
- Adult
- Age of Onset
- Asia
- Autoimmune Diseases
- Child
- Child, Preschool
- Colombia
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Ethnicity