Article
HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus.
Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Dec 1993
Wang H, He R
Abstract excerpt
Insulin-dependent diabetes mellitus (IDDM) is strongly associated with the presence of arginine in position 52 of the DQ alpha chain and absence of aspartic acid in position 57 of the DQ beta chain in Caucasians. With the aim of confirming this association in Chinese, extensive oligonucleotide dot blot hybridization of PCR-amplified DQA1 and DQB1 genes was studied using samples from 48 IDDM patients and 46...
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