HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus.

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Article

HLA-DQA and DQB alleles contribute to susceptibility to insulin-dependent diabetes mellitus.

Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih - 1 Dec 1993

Wang H, He R

Abstract excerpt

Insulin-dependent diabetes mellitus (IDDM) is strongly associated with the presence of arginine in position 52 of the DQ alpha chain and absence of aspartic acid in position 57 of the DQ beta chain in Caucasians. With the aim of confirming this association in Chinese, extensive oligonucleotide do...

Topics

Alleles
Asian People
Base Sequence
Diabetes Mellitus, Type 1
Disease Susceptibility
Genetic Variation
HLA-DQ Antigens
HLA-DQ alpha-Chains
HLA-DQ beta-Chains
Homozygote
Humans
Molecular Sequence Data
Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 8032070

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8032070-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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