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Article

HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: application of the haplotype method.

American journal of human genetics - 1 Mar 1997

Valdes A M, McWeeney S, Thomson G

Abstract excerpt

Insulin-dependent diabetes mellitus (IDDM) HLA class II DRB1-DQA1-DQB1 data from four populations (Norwegian, Sardinian, Mexican American, and Taiwanese) have been analyzed to detect the amino acids involved in the disease process. The combination of sites DRB1#67 and 86; DQA1#47; and DQB1#9, 26,...

Topics

Amino Acids
Diabetes Mellitus, Type 1
Disease Susceptibility
Gene Frequency
Genetic Predisposition to Disease
Genetic Techniques
HLA-DQ Antigens
HLA-DR Antigens
HLA-DRB1 Chains
Haplotypes
Humans
Incidence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Models, Genetic

Models, Statistical

Predictive Value of Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 9042932
PMCID: PMC1712519

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9042932-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: application of the haplotype method.PMID 9042932Read ↗

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