Article
HLA class II DR-DQ amino acids and insulin-dependent diabetes mellitus: application of the haplotype method.
American journal of human genetics - 1 Mar 1997
Valdes A M, McWeeney S, Thomson G
Abstract excerpt
Insulin-dependent diabetes mellitus (IDDM) HLA class II DRB1-DQA1-DQB1 data from four populations (Norwegian, Sardinian, Mexican American, and Taiwanese) have been analyzed to detect the amino acids involved in the disease process. The combination of sites DRB1#67 and 86; DQA1#47; and DQB1#9, 26, 57, and 70 predicts the IDDM component in these four populations, when the results and criteria of the haplotype...
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