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Article

Reevaluation of the importance of polymorphic HLA class II alleles and amino acids in the susceptibility of individuals of different populations to type I diabetes.

American journal of medical genetics - 5 Mar 1998

Zamani M, Cassiman J J

Abstract excerpt

Several publications have shown that certain alleles at the HLA-DRB1, -DQA1, and -DQB1 loci are associated with insulin-dependent diabetes mellitus (IDDM). Many of these studies have claimed that HLA-DQalpha1Arg52 and DQbeta1Asp57 showed the strongest association with IDDM, but these results could not be confirmed in different populations. We have recently found that DRbeta1Lys71+ provided major susceptibility to...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9511982
DOI: 10.1002/(sici)1096-8628(19980305)76:2<183::aid-ajmg12>3.0.co;2-h

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Reevaluation of the importance of polymorphic HLA class II alleles and amino acids in the susceptibility of individuals of different populations to type I diabetes.PMID 9511982Read ↗

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