Mutation rate of the CDKN2 gene in malignant gliomas.

Article

Mutation rate of the CDKN2 gene in malignant gliomas.

Cancer research - 15 Dec 1994

Giani C, Finocchiaro G

Abstract excerpt

The CDKN2 gene encodes p16, a protein controlling the cell cycle. CDKN2 is deleted in a relevant number of tumor cell lines, but results of the studies in primary tumors are contradictory. We have investigated by using quantitative polymerase chain reaction and single-strand conformation polymorp...

Topics

Base Sequence
Carrier Proteins
Cyclin-Dependent Kinase Inhibitor p16
Exons
Glioma
Humans
Molecular Sequence Data
Mutation
Polymerase Chain Reaction

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