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Article

Analysis of cyclin-dependent kinase inhibitor genes (CDKN2A, CDKN2B, andCDKN2C) in childhood rhabdomyosarcoma

1 Apr 1996

Abstract excerpt

p16INK4A, p15INK4B, and p18 proteins are highly specific inhibitors of cyclin-dependent serine/threonine kinase (CDK) activities required for GI-S transition in the eukaryotic cell division cycle. Mutations, mainly homozygous deletions, of the CDKN2A (p16INK4A/MTSI) gene have been recently found in tumor cell lines and in many primary tumors. We looked for homozygous deletions of CDKN2A, CDKN2B (p15INK4B), and...

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Identifiers

PMID: 8703847
DOI: 10.1002/(sici)1098-2264(199604)15:4<217::aid-gcc3>3.0.co;2-4

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Source receipt: pubmed, retrieved 7 Sept 2026.

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