CDKN2 mutation is infrequent in german hepatocellular carcinoma.

Abstract excerpt

For hepatocellular carcinoma, only scarce and controversial data on CDKN2 alterations are available. A high rate of mutations in a Chinese study contrasts with a low rate found in Japanese tumors and a CDKN2 germline mutation in 4/26 Swiss tumors examined. We analyzed 23 hepatocellular carcinomas from German patients for homozygous deletions of CDKN2 by coamplification with the human tyrosine hydroxylase (TH)...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carcinoma, Hepatocellular
• Share to Gene Deletion
• Share to Genes, Tumor Suppressor