Homologous recombination is required for the viability of rad27 mutants.

doi:10.1093/nar/26.24.5589

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Article

Homologous recombination is required for the viability of rad27 mutants.

Nucleic acids research - 15 Dec 1998

Symington L S

Abstract excerpt

The RAD27/RTH1 gene of Saccharomyces cerevisiae encodes a structural and functional homolog of the 5'-3' exonuclease function of Escherichia coli DNA polymerase I. Four alleles of RAD27 were recovered in a screen for hyper-recombination, a phenotype also displayed by polA mutants of E.coli. All f...

Topics

Checkpoint Kinase 1
Escherichia coli
Mutation
Protein Kinases
Recombination, Genetic
Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 9837987
DOI: 10.1093/nar/26.24.5589
PMCID: PMC148039

Genes

MRE11
RAD1
RAD50
RAD51

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RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9837987-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.