Article
Mono- and bi-allelic expression of insulin-like growth factor II gene in human muscle tumors.
Human molecular genetics - 1 Jul 1994
Pedone P V, Tirabosco R, Cavazzana A O, Ungaro P, Basso G, Luksch R, Carli M, Bruni C B, Frunzio R, Riccio A
Abstract excerpt
Insulin-like growth factor II (IGF-II) is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the...
Topics
- Adult
- Alleles
- Base Sequence
- Child
- Female
- Gene Expression Regulation, Neoplastic
- Genes
- Genomic Imprinting
- Humans
- Insulin-Like Growth Factor II
- Male
- Molecular Sequence Data
- Muscle Proteins
- Muscles
- Neoplasm Proteins
- Rhabdomyosarcoma
- Soft Tissue Neoplasms