Article
Abnormalities of insulin-like growth factor (IGF-I and IGF-II) genes in human tumor tissue.
Growth regulation - 1 Mar 1992
Schneid H, Seurin D, Noguiez P, Le Bouc Y
Abstract excerpt
Recent findings have indicated that Insulin-like growth factors (IGF-I and IGF-II) may play a role in neoplasia. Expression of their genes, which are highly complex structures, is tissue-specific and developmentally regulated. The purpose of the present study was to determine whether a relationsh...
Topics
- Alleles
- Blotting, Northern
- Blotting, Southern
- Carcinoma, Hepatocellular
- DNA, Neoplasm
- Deoxyribonucleases, Type II Site-Specific
- Fibroma
- Gene Expression Regulation, Neoplastic
- Humans
- Insulin-Like Growth Factor I
- Insulin-Like Growth Factor II
- Leiomyoma
- Leukocytes
- Liver Neoplasms
- Lymphoma, Non-Hodgkin
- Methylation
- Neuroblastoma
- Polymorphism, Restriction Fragment Length