Article
Abnormalities of insulin-like growth factor (IGF-I and IGF-II) genes in human tumor tissue.
Growth regulation - 1 Mar 1992
Schneid H, Seurin D, Noguiez P, Le Bouc Y
Abstract excerpt
Recent findings have indicated that Insulin-like growth factors (IGF-I and IGF-II) may play a role in neoplasia. Expression of their genes, which are highly complex structures, is tissue-specific and developmentally regulated. The purpose of the present study was to determine whether a relationship exists between tumorigenesis and the structure and expression of IGF genes. The structures of the IGF-I and IGF-II...
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