Article
Expression and parental imprinting of the H19 gene in human rhabdomyosarcoma.
Oncogene - 27 Mar 1997
Casola S, Pedone P V, Cavazzana A O, Basso G, Luksch R, d'Amore E S, Carli M, Bruni C B, Riccio A
Abstract excerpt
The expression of Insulin-like Growth Factor 2 (IGF-2) and H19, two genes located on human chromosome 11p15 and provided with cell growth modulating activity, is regulated by parental imprinting, in that the activity of their alleles is dependent on the parental origin. Parental bias in the genet...
Topics
- Alleles
- DNA-Binding Proteins
- Forkhead Box Protein O1
- Forkhead Transcription Factors
- Gene Expression Regulation, Developmental
- Gene Expression Regulation, Neoplastic
- Heterozygote
- Homeodomain Proteins
- Humans
- Insulin-Like Growth Factor II
- Muscle Neoplasms
- Muscle Proteins
- Muscles
- Nerve Tissue Proteins