Article
Retinoblastoma and p53 genes as prognostic indicators in urological oncology.
Urologia internationalis - 1 Jan 1994
Wolff J M, Stephenson R N, Jakse G, Habib F K
Abstract excerpt
Recent studies of the malignant phenotype have suggested that cumulative genetic changes are necessary for a malignant cell to develop. Alterations in particular genes associated with cell growth and division have been identified and two main classes of genes have been characterized. Oncogenes are those genes which when mutated promote tumour growth, whereas tumour suppressor genes (antioncogenes) inhibit tumour...
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