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Article

Analysis of key cell‐cycle checkpoint proteins in colorectal tumours

12 Feb 2002

Abstract excerpt

Aberrations in the components of cell-cycle checkpoints are a common feature of many tumours and several have been shown to have prognostic significance in colorectal cancer. In this study, seven components of cell-cycle control [cyclin D1, retinoblastoma (pRb), p21, p27, p16, p53, and proliferating cell nuclear antigen (PCNA)] were examined in a large series of well-characterized colorectal adenocarcinomas using...

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PMID: 11920733
DOI: 10.1002/path.1053

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