Article
Expression of regulatory proteins and proliferative activity in relation to phenotypic characteristics of upper urothelial carcinoma.
Vojnosanitetski pregled - 1 Jul 2011
Dolićanin Zana, Velicković Ljubinka Janković, Djordjević Biljana, Visnjić Milan, Pesić Ivana, Ristić Ana, Marjanović Vesna
Abstract excerpt
BACKGROUND/AIM: Deregulation of the normal cell cycle is common in upper urothelial carcinoma (UUC). The aim of this study was to investigate the expression of regulatory proteins of the cell cycle (p53, p16, cyclin D1, HER-2) and proliferative Ki-67 activity in UUC, and to determine their interaction and influence on the phenotypic characteristics of UUC. METHODS: In 44 patients with UUC, histopathological and...
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