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Article

Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3.

Journal of virology - 1 Sept 2008

Bruton Rachel K, Pelka Peter, Mapp Katie L, Fonseca Gregory J, Torchia Joseph, Turnell Andrew S, Mymryk Joe S, Grand Roger J A

Abstract excerpt

C-terminal binding protein (CtBP) binds to adenovirus early region 1A (AdE1A) through a highly conserved PXDLS motif close to the C terminus. We now have demonstrated that CtBP1 also interacts directly with the transcriptional activation domain (conserved region 3 [CR3]) of adenovirus type 5 E1A (Ad5E1A) and requires the integrity of the entire CR3 region for optimal binding. The interaction appears to be at...

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Identifiers

PMID: 18524818
DOI: 10.1128/JVI.00248-08
PMCID: PMC2519622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3.PMID 18524818Read ↗

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