Malignant phenotype correlating with drug resistance in two human neuroblastoma cell lines.

doi:10.1007/BF01306453

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Article

Malignant phenotype correlating with drug resistance in two human neuroblastoma cell lines.

Journal of neuro-oncology - 1 Jan 1994

Wollman Y, Shahar I, Goldstein M, Leibovici J

Abstract excerpt

The main cause for the failure of chemotherapeutic treatment of advanced cancer probably lies in the emergence of drug resistance clones. In the present study we compared the sensitivity to adriamycin (ADR) and the capacity of ADR uptake in two human neuroblastoma cell lines differing in properti...

Topics

Cell Differentiation
Cell Division
Cell Separation
Doxorubicin
Drug Resistance
Flow Cytometry
Humans
Microscopy, Fluorescence
Neoplasm Metastasis
Neuroblastoma
Phenotype
Tumor Cells, Cultured

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