Article
Invasive properties of multidrug resistant human melanoma cells.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia - 1 Jan 2005
Molinari A, Stringaro A, Gentile M, Colone M, Toccacieli L, Arancia G
Abstract excerpt
Melanoma cells exhibit a high level of intrinsic or acquired resistance to the cytotoxic agents often associated with the over-expression of drug transporters such as P-glycoprotein (P-gp). In this in vitro study, we investigated the possible relationship between P-gp and CD44, the cell adhesion molecule involved in metastasis and tumor progression of melanoma cells. CD44 expression appeared to be similar in the...
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