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Article

Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression.

International journal of oncology - 1 Oct 2005

Kotchetkov Rouslan, Driever Pablo Hernáiz, Cinatl Jaroslav, Michaelis Martin, Karaskova Jana, Blaheta Roman, Squire Jeremy A, Von Deimling Andreas, Moog Jussi, Cinatl Jindrich

Abstract excerpt

Acquisition of P-gp-mediated multidrug-resistance does not always correlate with observed malignant behavior of NB. To characterize alterations accompanying development of multidrug-resistance in NB we established two neuroblastoma cell sublines resistant to vincristine (UKF-NB-3rVCR10) and doxorubicin (UKF-NB-3rDOX20). UKF-NB-3rVCR10 and UKF-NB-3rDOX20 overexpressed functional P-gp and developed an increased...

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Identifiers

PMID: 16142320

Genes

MYCN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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