Article
Multidrug resistance and behavioural phenotype of cancer cells.
Cell biology international - 1 Oct 1993
Bashir I, Sikora K, Foster C S
Abstract excerpt
Resistance to cytotoxic chemotherapy is a major obstacle preventing successful treatment of cancer, allowing dissemination of tumour metastases, and may be viewed as the ultimate cause of death in the majority of patients with a malignant disease. Although cytotoxic chemotherapy is classically employed to produce maximal killing of malignant cells, the therapeutic doses of individual drugs required to achieve...
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