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Article

p53 Protein accumulates in Cushings adenomas and invasive non-functional adenomas.

The Journal of clinical endocrinology and metabolism - 1 Nov 1994

Buckley N, Bates A S, Broome J C, Strange R C, Perrett C W, Burke C W, Clayton R N

Abstract excerpt

The p53 protein, a negative regulator of cell growth, plays an important role in the pathogenesis of many human tumours following gene mutation and/or deletion. We screened a large number of sporadic pituitary tumours for p53 protein accumulation suggestive of gene mutation. Samples were divided...

Topics

Adenoma
Adenoma, Basophil
Adrenocorticotropic Hormone
Humans
Immunohistochemistry
Mutation
Pituitary Neoplasms
Tumor Suppressor Protein p53

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7962351
DOI: 10.1210/jcem.79.5.7962351

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7962351-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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