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Article

Absence of mutations in the p53 tumor suppressor gene in non-invasive Cushing adenomas.

Medicina - 1 Jan 1999

Copelli S B, Loza Coll M A, Bruno O D

Abstract excerpt

A lot of evidence supports the existence of a monoclonal origin for pituitary tumors, and several genetic alterations have already been confirmed as necessary or sufficient for unrestrained cellular growth and pituitary function. The p53 gene, a known tumor-suppressor gene (TSG), encodes a protein that exerts antiproliferative effects such as cell-growth arrest and apoptosis in response to several types of...

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Identifiers

PMID: 10684166

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Absence of mutations in the p53 tumor suppressor gene in non-invasive Cushing adenomas.PMID 10684166Read ↗

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