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Article

Activation of two new alpha(1,3)fucosyltransferase activities in Chinese hamster ovary cells by 5-azacytidine.

Cell regulation - 1 Dec 1991

Potvin B, Stanley P

Abstract excerpt

Several mammalian alpha(1,3)fucosyltransferases (alpha[1,3]Fuc-T) that synthesize carbohydrates containing alpha(1,3)fucosylated lactosamine units have been identified. Although Chinese hamster ovary (CHO) cells do not express alpha(1,3)Fuc-T activity, the rare mutants LEC11 and LEC12, isolated after mutagenesis or DNA transfection, each express an alpha(1,3)Fuc-T that may be distinguished by several criteria....

Topics

Animals
Azacitidine
CHO Cells
Carbohydrate Sequence
Cricetinae
Enzyme Activation
Fucosyltransferases
Lewis X Antigen
Molecular Sequence Data
Mutation
Oligosaccharides
Phenotype

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Identifiers

PMID: 1724918
DOI: 10.1091/mbc.2.12.989
PMCID: PMC361899

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VIM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1724918-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Activation of two new alpha(1,3)fucosyltransferase activities in Chinese hamster ovary cells by 5-azacytidine.PMID 1724918Read ↗

alpha(1,3)fucosyltransferases expressed by the gain-of-function Chinese hamster ovary glycosylation mutants LEC12, LEC29, and LEC30.Semantic proximity Read ↗

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