Article
BCL10 is not a major target for frequent loss of 1p in testicular germ cell tumors.
Cancer genetics and cytogenetics - 15 Apr 2001
Kakinuma H, Habuchi T, Ito T, Mishina M, Sato K, Satoh S, Akao T, Ogawa O, Kato T
Abstract excerpt
The deletion of chromosome 1p is one of the frequent genetic alterations found in testicular germ cell tumors (GCTs), suggesting the presence of a tumor suppressor gene. BCL10, which was identified as a gene altered in mucosa-associated lymphoid tissue lymphoma, has been mapped at 1p22. The gene has been reported to be mutated in a variety of human cancers. In this study, we investigated the allelic deletions on...
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