Article
Development of TGF-beta resistance during malignant progression.
Archives of pharmacal research - 1 Feb 1999
Kim Y S, Yi Y, Choi S G, Kim S J
Abstract excerpt
Transforming growth factor-beta (TGF-beta) is the prototypical multifunctional cytokine, participating in the regulation of vital cellular activities such as proliferation and differentiation as well as a number of basic physiological functions. The effects of TGF-beta are critically dependent on the expression and distribution of a family of TGF-beta receptors, the TGF-beta types I, II, and III. It is now known...
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