Article
Clonal analysis of neoplastic transformation in cultured diploid rat liver epithelial cells.
Basic life sciences - 1 Jan 1991
Grisham J W, Tsao M S, Lee L W, Smith G J
Abstract excerpt
Expression of TGF-alpha mRNA, which correlates well with the ability of cells to condition medium with an EGF-like activity, clonally segregates best with tumorigenicity among the several single phenotypes considered in this study. The results of unreported studies in which we have analyzed the q...
Topics
- Animals
- Biomarkers, Tumor
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Clone Cells
- DNA, Neoplasm
- Epithelium
- Gene Expression Regulation, Neoplastic
- Liver
- Methylnitronitrosoguanidine
- Mice
- Mice, Nude
- Neoplasm Proteins
- Neoplasm Transplantation
- Phenotype
- Rats
- Rats, Inbred F344