Article
High frequency of tumour cell reversion to non-tumorigenic phenotype.
European journal of cancer (Oxford, England : 1990) - 1 Jan 1992
Lavrovsky V A, Guvakova M A, Lavrovsky Y V
Abstract excerpt
Nine spontaneously transformed cell lines were isolated from embryo fibroblasts of mice and rats with different genotypes. In six cell lines highly tumorigenic cell variants were selected. At the start of culture all cell lines were of low or zero tumorigenicity. The same cells in a confluent mon...
Topics
- Animals
- Cell Line
- Cell Transformation, Neoplastic
- Clone Cells
- Cytotoxicity Tests, Immunologic
- Fibroblasts
- Growth Substances
- Macrophages
- Mice
- Mice, Inbred Strains
- Mitosis
- Phenotype
- Rats
- Rats, Inbred Strains
- Time Factors
- Tumor Cells, Cultured