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Article

p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells.

Breast cancer research and treatment - 1 Jan 1994

Eliyahu D, Evans S, Rosen N, Eliyahu S, Zwiebel J, Paik S, Lippman M

Abstract excerpt

One common step in the malignant progression of a wide variety of human cancers seems to be inactivation of the p53 gene, via point mutation or deletion or both; or overexpression of mutated protein with dominant transforming activity. This study shows a suppressive effect of wild type p53 on the growth of human breast cancer cells. Introduction of wild type p53 versus mutant into five human breast cancer cell...

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Identifiers

PMID: 7949216
DOI: 10.1007/BF00666061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells.PMID 7949216Read ↗

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The role of p53 in the normal control of cell proliferation.Semantic proximity Read ↗

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