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Article

The role of p53 in the normal control of cell proliferation.

Current opinion in cell biology - 1 Apr 1991

Milner J

Abstract excerpt

The regulation of cell proliferation involves p53. A mutant allele of p53, p53-Val135, has been found to be temperature-sensitive for function with separable suppressor and promoter effects on cell proliferation. These opposing suppressor and promoter functions of p53 correlate with two alternative, temperature-sensitive conformations of the p53-Val135 polypeptide.

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Source

Identifiers

PMID: 1953903
DOI: 10.1016/0955-0674(91)90153-p

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of p53 in the normal control of cell proliferation.PMID 1953903Read ↗

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