Article
The different expression patterns of interleukin-1 receptor antagonist in systemic lupus erythematosus.
Tissue antigens - 1 Dec 2006
Tsai L-J, Lan J-L, Lin C-Y, Hsiao S-H, Tsai L-M, Tsai J-J
Abstract excerpt
The interleukin-1 receptor antagonist (IL1RN or IL-1Ra) is a natural antagonist of IL-1-beta. Using IL1RN as a possible marker in patients with systemic lupus erythematosus (SLE), we evaluated whether uIL1RN single nucleotide polymorphisms (SNPs) were associated with the pathogenesis of SLE in Taiwanese, and specifically whether IL1RN (rs315952) was significantly associated with end-stage renal disease. We...
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