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Article

Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene.

The Journal of investigative dermatology - 1 Sept 1994

Tarlow J K, Clay F E, Cork M J, Blakemore A I, McDonagh A J, Messenger A G, Duff G W

Abstract excerpt

One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1. Its actions are regulated by a structurally related anti-inflammatory cytokine known as the interleukin-1 receptor antagonist. We have previously characterized a DNA polymorphism in this gene (IL-1rn) an...

Topics

Alleles
Alopecia
Cytokines
Genes
Humans
Polymorphism, Genetic
Receptors, Interleukin-1
Repetitive Sequences, Nucleic Acid

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8077705
DOI: 10.1111/1523-1747.ep12395398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8077705-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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