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Article

Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene.

The Journal of investigative dermatology - 1 Sept 1994

Tarlow J K, Clay F E, Cork M J, Blakemore A I, McDonagh A J, Messenger A G, Duff G W

Abstract excerpt

One of the most potent pro-inflammatory mediators is the early-acting cytokine interleukin-1. Its actions are regulated by a structurally related anti-inflammatory cytokine known as the interleukin-1 receptor antagonist. We have previously characterized a DNA polymorphism in this gene (IL-1rn) and have found associations between allele 2 and several chronic inflammatory diseases. In the present study, we tested...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8077705
DOI: 10.1111/1523-1747.ep12395398

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Severity of alopecia areata is associated with a polymorphism in the interleukin-1 receptor antagonist gene.PMID 8077705Read ↗

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