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Article

Meta-analysis of associations of IL1 receptor antagonist and estrogen receptor gene polymorphisms with systemic lupus erythematosus susceptibility.

PloS one - 1 Jan 2014

Cai Li, Zhang Jin-wei, Xue Xing-xin, Wang Zhi-gang, Wang Jia-jia, Tang Shai-di, Tang Shao-wen, Wang Jie, Zhang Yun, Xia Xian

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease that affects a number of different organs and tissues. Interleukin-1 (IL1) and estrogen are considered potential elements in the pathology of SLE. Recently, the variable number of tandem repeats (VNTR) polymorphism in the IL1 receptor antagonist gene (IL1-RN) and PvuII (rs2234693) and XbaI (rs9340799) polymorphisms in the estrogen receptor 1 gene (ESR1)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ESR1 gene
Share to Genetic Predisposition to Disease
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Share to Lupus Erythematosus, Systemic
Share to Polymorphism, Genetic
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Source

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Identifiers

PMID: 25286391
DOI: 10.1371/journal.pone.0109712
PMCID: PMC4186846

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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