Article
The efficiency of mapping of quantitative trait loci using cofactor analysis in half-sib design.
Genetics, selection, evolution : GSE - 1 Jan 2000
Sahana Goutam, de Koning Dirk Jan, Guldbrandtsen Bernt, Sørensen Peter, Lund Mogens Sandø
Abstract excerpt
This simulation study was designed to study the power and type I error rate in QTL mapping using cofactor analysis in half-sib designs. A number of scenarios were simulated with different power to identify QTL by varying family size, heritability, QTL effect and map density, and three threshold levels for cofactor were considered. Generally cofactor analysis did not increase the power of QTL mapping in a half-sib...
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