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Article

Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data.

American journal of human genetics - 1 May 2000

Sham P C, Cherny S S, Purcell S, Hewitt J K

Abstract excerpt

Optimal design of quantitative-trait loci (QTL) mapping studies requires a precise understanding of the power of QTL linkage versus QTL association analysis, under a range of different conditions. In this article, we investigate the power of QTL linkage and association analyses for simple random sibship samples, under the variance-components model proposed by Fulker et al. After a brief description of an...

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Identifiers

PMID: 10762547
DOI: 10.1086/302891
PMCID: PMC1378020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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