Article
Interactions between the Escherichia coli cyclic AMP receptor protein and RNA polymerase at class II promoters.
Molecular microbiology - 1 Nov 1993
West D, Williams R, Rhodius V, Bell A, Sharma N, Zou C, Fujita N, Ishihama A, Busby S
Abstract excerpt
The effects of a number of mutations in crp have been measured at different cyclic AMP receptor protein (CRP)-dependent Class II promoters, where the CRP-binding site is centred around 41 1/2 base pairs upstream from the transcription start point. The amino acid substitutions HL159 and TA158 result in reduced CRP-dependent activation, but the reduction varies from one Class II promoter to another. Deletions in...
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