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Article

Transcription activation by the Escherichia coli cyclic AMP receptor protein: determinants within activating region 3.

Journal of molecular biology - 2 Jun 2000

Rhodius V A, Busby S J

Abstract excerpt

At Class II CRP-dependent promoters, the Escherichia coli cyclic AMP receptor protein (CRP) activates transcription by making multiple interactions with RNA polymerase (RNAP). Two discrete surfaces of CRP, known as Activating Region 1 (AR1) and Activating Region 2 (AR2), interact with the C-terminal and N-terminal domains, respectively, of the alpha subunit of RNAP. Activating Region 3 (AR3) is a third separate...

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Identifiers

PMID: 10860739
DOI: 10.1006/jmbi.2000.3736

Genes

CRP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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