Article
Identification of the CRP regulon using in vitro and in vivo transcriptional profiling.
Nucleic acids research - 1 Jan 2004
Zheng Dongling, Constantinidou Chrystala, Hobman Jon L, Minchin Stephen D
Abstract excerpt
The Escherichia coli cyclic AMP receptor protein (CRP) is a global regulator that controls transcription initiation from more than 100 promoters by binding to a specific DNA sequence within cognate promoters. Many genes in the CRP regulon have been predicted simply based on the presence of DNA-binding sites within gene promoters. In this study, we have exploited a newly developed technique, run-off...
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