An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms.

doi:10.1002/path.1711720104

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Article

An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms.

The Journal of pathology - 1 Jan 1994

Baas I O, Mulder J W, Offerhaus G J, Vogelstein B, Hamilton S R

Abstract excerpt

Immunohistochemical detection of intranuclear p53 gene product may indicate mutation of the p53 suppressor gene on chromosome 17p. We used six commercially available antibodies for p53 immunohistochemistry on 19 archival colorectal neoplasms and compared the results with the mutation status of th...

Topics

Antibodies
Antibodies, Monoclonal
Colonic Neoplasms
Genes, p53
Humans
Immunohistochemistry
Mutation
Neoplasm Proteins
Rectal Neoplasms
Tumor Suppressor Protein p53

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