Utility of cytokeratin 7 and 20 subset analysis as an aid in the identification of primary site of origin of malignancy in cytologic specimens.

doi:10.1002/(sici)1097-0339(199902)20:2<63::aid-dc3>3.0.co;2-k

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Article

Utility of cytokeratin 7 and 20 subset analysis as an aid in the identification of primary site of origin of malignancy in cytologic specimens.

Diagnostic cytopathology - 1 Feb 1999

Blumenfeld W, Turi G K, Harrison G, Latuszynski D, Zhang C

Abstract excerpt

This study was undertaken to assess the utility of combined cytokeratin (CK) 7/20 immunoprofile determination in malignant cytologic cell blocks as an aid to the identification of tumor primary site of origin. Fifty-one cases in which CK 7/20 immunocytochemistry was performed as part of the initi...

Topics

Biomarkers
Biopsy
Humans
Immunohistochemistry
Intermediate Filament Proteins
Keratin-20
Keratin-7
Keratins
Neoplasms
Phenotype

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