Article
P53 and radiotherapy for oesophageal carcinoma: A comparison between 4 different antibodies.
Oncology reports - 1 Jan 2000
Pomp J, Blom J, Zwinderman A H, Van Krimpen C
Abstract excerpt
Wild-type p53 protein plays an important role in the cellular response to ionising radiation and other DNA damaging agents and is mutated in many human tumours. Immunohistochemistry is a rapid method to detect elevated protein levels. The p53 status in a group of patients treated by radiotherapy exclusively for oesophagus carcinoma was examined and correlated with pre-treatment parameters and treatment outcome...
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