Differences in the expression of p53 protein in oral lichen planus based on the use of monoclonal antibodies DO7 and pAb 240.

doi:10.1016/j.oraloncology.2007.06.013

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Article

Differences in the expression of p53 protein in oral lichen planus based on the use of monoclonal antibodies DO7 and pAb 240.

Oral oncology - 1 May 2008

Gonzalez-Moles M A, Gil-Montoya J A, Ruiz-Avila I, Esteban F, Bascones-Martinez A

Abstract excerpt

UNLABELLED: A comparison is made of p53 expression in oral lichen planus, detected via monoclonal antibodies pAb240 and DO7, and with cell apoptosis and proliferation markers. An immunohistochemical study was made of 51 cases of oral lichen planus and 26 controls, using monoclonal antibodies DO7 and pAb240, anti-caspase-3 antibody and Mib-1 antibody against Ki-67. The cases showed important p53 expression with...

Topics

Adult
Aged
Antibodies, Monoclonal
Apoptosis
Case-Control Studies
Caspase 3
Female
Humans
Immunohistochemistry
Ki-67 Antigen
Lichen Planus, Oral
Male
Middle Aged
Mutation
Tumor Suppressor Protein p53

Source

Open in PubMed

Identifiers

PMID: 17826304
DOI: 10.1016/j.oraloncology.2007.06.013

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