Article
Characterization of a cell mutant specifically defective in the synthesis of anticoagulantly active heparan sulfate.
The Journal of biological chemistry - 7 Oct 1994
Colliec-Jouault S, Shworak N W, Liu J, de Agostini A I, Rosenberg R D
Abstract excerpt
We have investigated the characteristics of clonal L cell mutant VI-7 that has previously been demonstrated to exhibit reduced levels of cell surface proteoglycans containing heparan sulfate (HS) with regions of defined monosaccharide sequence that interact with antithrombin (HSact) (de Agostini,...
Topics
- Animals
- Anticoagulants
- Heparitin Sulfate
- L Cells
- Membrane Glycoproteins
- Mice
- Mutation
- Proteoglycans
- Syndecan-4