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Article

Independence of type I angiotensin II receptor endocytosis from G protein coupling and signal transduction.

The Journal of biological chemistry - 7 Oct 1994

Hunyady L, Baukal A J, Balla T, Catt K J

Abstract excerpt

The relationship between angiotensin II-induced activation of G proteins and receptor internalization was analyzed by transiently expressing mutant and wild type cDNAs for the rat AT1a receptor in COS-7 cells. Pertussis toxin-sensitive G proteins did not appear to play a role in endocytosis since the receptor showed normal internalization kinetics in pertussis toxin-treated cells. Three deletion mutants of the...

Topics

Angiotensin II
Animals
Cell Line
Endocytosis
GTP-Binding Proteins
Inositol Phosphates
Mutation
Rats
Receptors, Angiotensin
Signal Transduction

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PMID: 7929158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7929158-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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