Article
Phosphorylation of the angiotensin II (AT1A) receptor carboxyl terminus: a role in receptor endocytosis.
Molecular endocrinology (Baltimore, Md.) - 1 Oct 1998
Thomas W G, Motel T J, Kule C E, Karoor V, Baker K M
Abstract excerpt
The molecular mechanism of angiotensin II type I receptor (AT1) endocytosis is obscure, although the identification of an important serine/threonine rich region (Thr332Lys333Met334Ser335Thr336Leu337 Ser338) within the carboxyl terminus of the AT1A receptor subtype suggests that phosphorylation ma...
Topics
- Angiotensin II
- Angiotensin Receptor Antagonists
- Animals
- CHO Cells
- Cricetinae
- Endocytosis
- Epitopes
- Mutation
- Peptide Fragments
- Phosphorus Radioisotopes
- Phosphorylation
- Precipitin Tests
- Receptor, Angiotensin, Type 1
- Receptors, Angiotensin