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Article

Atypical signaling and functional desensitization response of MAS receptor to peptide ligands.

PloS one - 1 Jan 2014

Tirupula Kalyan C, Desnoyer Russell, Speth Robert C, Karnik Sadashiva S

Abstract excerpt

MAS is a G protein-coupled receptor (GPCR) implicated in multiple physiological processes. Several physiological peptide ligands such as angiotensin-(1-7), angiotensin fragments and neuropeptide FF (NPFF) are reported to act on MAS. Studies of conventional G protein signaling and receptor desensitization upon stimulation of MAS with the peptide ligands are limited so far. Therefore, we systematically analyzed G...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25068582
DOI: 10.1371/journal.pone.0103520
PMCID: PMC4113456

Genes

NPFF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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